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Metrics details. Neurological manifestations associated with COVID remain partially described, mainly in low- and middle-income countries where diagnostic tools are limited. To address this, we assembled medical centers in Brazil with the goal of describing neurological syndromes associated with COVID during the first wave of the pandemic. From June 1st, to June 1st, , non-consecutive adult patients with new onset of six neurological syndromes up to 60 days after confirmed COVID were included.
Data were compiled from four tertiary centers and compared with general local COVID data, as well as with a previous cohort focused on vascular syndrome. The median time from COVID to onset of neurological symptoms was 14 days, suggesting a post-infectious immune-mediated mechanism. Among all neurological syndromes, vascular syndromes were the most common, and their severity surpassed that of vascular syndromes not attributed to COVID Peer Review reports.
Throughout history, viral emergencies have consistently exhibited an intriguing association with concurrent neurological manifestations [ 1 ].
It is noteworthy that these neurological sequelae, although not typically the primary syndrome characterizing an epidemic, frequently emerge as a striking and critical facet, demanding specialized medical attention [ 2 ]. As our understanding of the novel coronavirus, SARS-CoV-2, progressed and global infection rates rose, these neurological presentations transitioned from sporadic symptoms to worrisome syndromes that have yet to be fully characterized [ 4 ].
And while these numbers have been publicized and been the focus of a combination of political and social challenges [ 6 , 7 ], the potential long-term health issues associated with COVID, such as neurological, cardiovascular, and musculoskeletal problems were consistently overlooked.