Official websites use. Share sensitive information only on official, secure websites. Correspondence: berardino. Tight margins and high dose gradients are needed, and the precise localization of the target is mandatory. This device consists of an integrated Foley catheter with a transmitter connected to a receiver placed on the treatment table. A simulation CT scan was conducted while the patients had a filled bladder — cc and an empty rectum, and an EM tracking device was used.
The same rectal and bladder conditions were employed during the treatment. The patients received When the signals exceeded a 2 mm threshold in any of the three spatial directions, the treatment was manually interrupted. Results: We analyzed data about fractions. A small number of fractions showed a motion exceeding the predefined 2 mm threshold, which would have otherwise gone undetected without intrafraction motion management.
Keywords: prostate cancer, stereotactic body radiation therapy SBRT , extreme hypofractionation, image-guided radiation therapy IGRT , intrafraction motion mitigation, real-time electromagnetic tracking. Accordingly, PCa could benefit from hypofractionated regimens of radiation therapy RT [ 1 , 2 , 3 , 4 , 5 ].
Based on the recent major technological advances, RT can now be delivered with better organs-at-risk OARs sparing and prostate irradiation. Moreover, these improvements have also allowed the introduction of extreme hypofractionation using stereotactic body radiation therapy SBRT for PCa: even after long follow-up times, this therapeutic approach showed optimal results both in terms of biochemical control and side effects [ 6 , 7 ].
High dose gradients and the narrowest margins are employed in SBRT. Intrafraction prostate motion, mainly occurring due to rectal and bladder filling, is a major issue with respect to PCa SBRT [ 12 , 13 , 14 ]. Lovelock et al. Usually, such strategies are based on the implantation of intraprostatic fiducials. One of the limits of these devices is that they are radiopaque and interfere, via their artifacts, with the quality of imaging modalities e.
