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About Rheumatoid Arthritis: It is an autoimmune and inflammatory disease, wherein the immune system attacks healthy cells in the body by mistake, and causing inflammation in the affected parts of the body. The specific causes of RA are unknown. It mainly attacks the joints , usually many joints at once. RA commonly affects joints in the hands, wrists, and knees. Symptoms: In a joint with RA, the lining of the joint becomes inflamed, causing damage to joint tissue. This tissue damage can cause long-lasting or chronic pain, unsteadiness lack of balance , and deformity misshapenness.
It can also affect other tissues throughout the body and cause problems in organs such as the lungs, heart, and eyes. Treatment: Its treatment usually includes the use of medications that slow disease and prevent joint deformity, called disease-modifying antirheumatic drugs DMARDs. Key points of the research: Researchers have developed a smart system that responds directly to the biochemical signals in the inflamed synovial environment.
The system uses specially designed microspheres loaded with methotrexate , a commonly used anti-rheumatic drug. The formulation consists of polymer-lipid hybrid micro-composites , where the lipid component soya lecithin ensures high drug encapsulation efficiency, and the polymer component gelatin provides responsiveness to Matrix metalloproteinases MMP.
Click to View More. Visit Detail Page. Researchers have discovered huge landforms deep beneath the North Sea that suggest the region was swallowed by a giant ice sheet toward the middle of the last ice age. It is considered to be a marginal sea of the Atlantic Ocean. It connects to the Baltic Sea in the east via the Kattegat and Skagerrak straits. It covers an area of approximately , sq. It is one of the most i mportant fishing grounds globally.
Source : Giant ice age landforms discovered deep beneath North Sea revealed in amazing detail. The Union Budget announced the Gyan Bharatam Mission, under which one crore manuscripts will be conserved and documented.