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Official websites use. Share sensitive information only on official, secure websites. Their clinical potential in both central and peripheral nervous systems is illustrated meticulously related to typical diseases. The challenges relative to biosafety and scaled production as well as their future perspectives are also discussed in detail.
Typical instances as well as challenges and perspectives are provided to reveal the clinical translation values of TSPCI. In ingenious human nervous systems, over 14 billion neurons collaborate exquisitely and constitute intricate neural networks to perform a myriad of neurophysiological activities including sensation, motor, memory, and emotion. Currently, drug therapy and physical neuromodulation have been recognized as mainstream strategies for the clinical intervention of NDs.
For instance, the electrical signals conduct fleetly through nerve fibers coated with insulated myelin to avert mutual interference, [ 14 ] and the neurotransmitters are released at quantized doses with minimal diffusion between synaptic cleft to exert localized function.
Importantly, from the view of bionics, it is highly advisable to exploit neoteric intervention strategies which are qualified for playing pinpoint curative effects at lesions with negligible impact on surrounding healthy tissue.
Actualizing these assumptions is pressingly demanding, but fortunately, conquering the critical NDs and satisfying precision medicine have been set as significant goals of neuroscience.
