Official websites use. Share sensitive information only on official, secure websites. Correspondence , Jasmin M. Email: kizilirmak uni-hildesheim. Email: bjoern-hendrik. The default mode network DMN typically exhibits deactivations during demanding tasks compared to periods of relative rest. In functional magnetic resonance imaging fMRI studies of episodic memory encoding, increased activity in DMN regions even predicts later forgetting in young healthy adults.
This association is attenuated in older adults and, in some instances, increased DMN activity even predicts remembering rather than forgetting. Lastly, older adults with higher mPerAF in the DMN at rest tend to show higher memory performance, pointing towards the importance of a maintained ability to modulate DMN activity in old age.
The default mode network DMN; Buckner et al. Compared to young individuals, older adults typically show reduced deactivations of DMN structures like the mPFC and the precuneus during various cognitive tasks, including successful episodic encoding, working memory, or semantic categorization Hayes et al.
This finding is commonly thought to reflect the decreased ability of older adults to direct resources towards the taskβaway from spontaneous inwardly directed thought. In the present study, we aimed to elucidate the relationship between DMN activity at rest and during successful memory encoding in young and older adults.
Specifically, we aimed to assess whether there was a direct relationship between activity variation in DMN structures at rest and during successful encoding and whether such a relationship was related to age. This seems to be more readily explained by a targeted compensatory encoding mechanism, which would be in line with a study by Turner and Spreng who reported functional connectivity increases between lateral PFC and DMN regions during cognitively demanding tasks in older, but not in younger adults.
