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Official websites use. Share sensitive information only on official, secure websites. Corresponding author: Laura A. Little is known about rates and determinants of oral human papillomavirus HPV infection, an infection that is etiologically linked with oropharyngeal cancers.
A cohort of male university students 18β24 years of age was examined every 4 months men; visits. Data on potential determinants was gathered via clinical examination, in-person questionnaire, and biweekly online diary. Hazard ratios HR were used to measure associations with incident infection. Prevalence of oral HPV infection at enrollment was 7.
Prevalence of oral HPV was 2. HPV was not common. Sexual contact and autoinoculation appeared to play independent roles in the transmission of alpha-genus HPV to the oral cavity of young men. Human papillomavirus HPV is an etiologic agent for oropharyngeal cancers, with the strongest associations observed for cancer of the tonsils.
The variability has been attributed to differences in study populations and approaches to specimen collection, processing, and testing.
Although transmission of HPV to the oral cavity and oropharynx is hypothesized to occur mainly through sexual contact, determinants of acquisition have not been fully established through longitudinal studies. Cross-sectional associations between prevalent oral HPV infection and sexual behaviors, such as higher numbers of vaginal sex partners or oral sex partners, have been observed in some studies, 8 β 11 but not others.